产品货号：
Z26081
中文名称：
RTN3抗体
英文名称：
Anti-RTN3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RTN3 Antibody |
| 指标别名 | ASYIP,HAP,NSP like protein 2,NSP like protein II,NSPL2,NSPLII,reticulon 3,RTN3,RTN3 A1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | RTN3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human RTN3(1017-1032aa EKIQAKLPGIAKKKAE),identical to the related mouse and rat sequences. |
| 实际分子量 | 113KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Reticulon-3,also known as RTN3 or NSPL2,is a protein that in humans is encoded by the RTN3 gene.It is mapped to 11q13,which is between markers D11S4535 and D11S4627.This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues.This family of proteins interact with,and modulate the activity of beta-amyloid converting enzyme 1(BACE1),and the production of amyloid-beta.RTN3 colocalized with BACE1 in neurons of human brain gray matter,and overexpression of RTN3 in vitro inhibited BACE1 activity and decreased amyloid precursor protein processing. |
| Uniprot ID | O95197 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | reticulon 3 |
| 蛋白名全称 | Reticulon-3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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